Preamble: ‘Look at me’ -- 1 Healthy Volunteering: The Concept of Volunteering in Phase I Clinical drug trials in the UK -- 2 Risk, Rewards and Rational Consent in Healthy Volunteering -- 3 Risk, Motivation and Decision Making in Everyday life: A Phenomenological Approach -- 4 Who takes part in clinical drug trials? -- 5 ‘Context is Everything’: - The Reality of Becoming a Human Guinea Pig -- 6 Economic exchanges? Healthy Volunteering as a Form of Labour -- 7 Volunteering for Free is Dead, Long live Reciprocity? Revisiting the Gift Relationship -- 8 When human beings become guinea pigs.This book provides a richly detailed contribution to the understanding of healthy volunteer experiences in clinical drug trials in the UK. Contemporary society, especially the West, has seen a significant increase in the production and use of pharmaceutical products, particularly for disease treatment. However, despite the large numbers of people involved, particularly in the UK, very little is known about their experiences in commercial phase I clinical drug trials. Shadreck Mwale critiques common conceptions of the terms ‘volunteer’ and ‘altruism’ as used in policy and practice of human involvement in clinical trials and calls for an awareness of the complexity of the terms and how the social contexts participants find themselves in shape acts of voluntarism. Based on extensive empirical evidence and conceptual analysis, the book presents new insights into the lives of healthy volunteers, challenges bioethical conceptions and generates new frameworks for policy and practice of FIHCTs. It will be of particular interest to scholars and practitioners in the wider social sciences, medical Sociology and medical anthropology, pharmacology and bioethics.