History of Gastric Carcinoma Research -- History of Gastric Carcinoma Research in Japan: Basic Aspects -- Historical Review of Research and Treatment of Gastric Cancer in Japan: Clinical Aspect -- Recent Advances in Molecular Carcinogenesis in Gastric Carcinoma -- Recent Advances in Molecular Pathobiology of Gastric Carcinoma -- Pathogenesis and Pathology -- Helicobacter pylori and Gastric Carcinoma -- Fundic Mucosal Change Associated with Oxyntic Atrophy -- DNA Methylation and Gastric Carcinoma -- Distinction of High-Grade Intraepithelial Neoplasia and Tubular Gastric Adenocarcinoma -- Histological Diversity of Early Gastric Carcinoma -- Epstein-Barr Virus-Associated Gastric Carcinoma -- Hepatoid Adenocarcinoma of the Stomach: Biological Significance of Hepatic Transdifferentiation in Adenocarcinoma Cells -- Oncocytic Adenocarcinoma of the Stomach: Comparison with Parietal Cell Carcinoma -- Gastric Carcinoma in the Elderly -- Adenocarcinoma with Gastric Mucin Phenotype -- Clinical Diagnosis -- Endoscopic Diagnosis of Gastric Carcinoma -- Ultrasonic Diagnosis of Gastric Cancer -- Recent Advances in Radiology for the Diagnosis of Gastric Carcinoma -- Therapy for Gastric Carcinoma -- The Gastric Cancer Treatment Guideline -- Endoscopic Resection for Early Gastric Cancer -- Current Treatment Strategies for Early Gastric Cancer -- Surgery for Advanced Gastric Cancer -- Laparoscopic Gastrectomy -- Chemotherapy for Advanced Unresectable Gastric Cancer -- Adjuvant or Neoadjuvant Chemotherapy Against Advanced Gastric Carcinoma -- Recent Topics in Gastric Carcinoma Research -- Micrometastasis of Gastric Cancer -- Sentinel Node Navigation Surgery: Application to Minimally Invasive and Function-Preserving Surgery for Early Gastric Cancer.Japan has long been a leader of research into the carcinogenesis, pathology, diagnosis, and treatment of gastric carcinoma, which is still the second leading cause of cancer death worldwide. Distinguished experts in the field collaborated in creating this groundbreaking work, providing a comprehensive view of gastric cancer. This book encourages further development of gastric cancer research and its clinical application. Topics include all aspects of gastric carcinoma, such as the history of clinical and experimental gastric cancer research; updated issues of molecular and pathological research on gastric carcinogenesis; multidisciplinary methods in diagnosis, treatment, and chemotherapy; and perspectives in minimally invasive surgery. Color figures of histological specimens and other clinical features assist readers in readily understanding the textual descriptions, making this volume a valuable source for clinicians and researchers alike.