Primary Prevention of Genetic Disorders and Place of Preimplantation Genetic Diagnosis -- Approaches to Preimplantation Genetic Diagnosis -- Preimplantation Genetic Diagnosis for Single Gene Disorders -- Preimplantation HLA Typing -- Preimplantation Genetic Diagnosis for Chromosomal Disorders -- Clinical Outcomes Following Preimplantation Genetic Diagnosis -- Preimplantation Genetic Diagnosis and Establishment of Human Embryonic Stem Cell Lines -- Ethical, Social, and Legal Issues.Although treatment is the major goal in the control of genetic disease, this is not yet a reality for most of inherited conditions. Even with the dramatic advancement in field of gene therapy, there are unfortunately not enough success stories to allow us to predict its impact in the near future. Preimplantation genetic diagnosis (PGD) offers the answer to the control of these inherited conditions by predicting reproductive outcome. It is no longer an experimental procedure, having become an integral part of genetic practices and assisted reproduction technology. This practical book is a vital new addition to the literature for fertility clinicians providing a comprehensive description of available experience, indications, methods and clinical outcomes. The authors of this book, from the Reproductive Genetics Institute in Chicago, USA, are among the leaders in this break-through field. Within this book, they instruct readers of the core features of the practice of PGD, while also providing incredibly detailed instructions of the genetics of a wide variety of common and not so common disorders that can be identified with the technique. This thorough and illuminating coverage ensures that this is the definitive reference book for those fertility specialists wishing to set up or already run a PGD clinic.