The Aetiopathology of Pressure Ulcers: A Hierarchical Approach -- Medical Perspectives in the 21st Century -- Medico-Legal Implications -- Patients at Risk for Pressure Ulcers and Evidence-Based Care for Pressure Ulcer Prevention -- The Measurement of Interface Pressure -- Susceptibility of Spinal Cord-Injured Individuals to Pressure Ulcers -- Prevention and Treatment of Pressure Ulcers Using Electrical Stimulation -- Biochemical Status of Soft Tissues Subjected to Sustained Pressure -- Stump-Socket Interface Conditions -- Perspectives of Numerical Modelling in Pressure Ulcer Research -- Skin Morphology and Its Mechanical Properties Associated with Loading -- Compression-Induced Tissue Damage: Animal Models -- The Role of Oxidative Stress in the Development and Persistence of Pressure Ulcers -- Transport of Fluid and Solutes in Tissues -- Skin Model Studies -- In Vitro Muscle Model Studies -- Imaging Tissues for Pressure Ulcer Prevention -- Magnetic Resonance Imaging and Spectroscopy of Pressure Ulcers -- Microelectrodes and Biocompatible Sensors for Skin pO2 Measurements -- New Tissue Repair Strategies.This book provides an up-to-date scientific account of all aspects related to pressure ulcers and pressure ulcer research, as well as evidence-based knowledge of pressure ulcer aetiology. Further, it describes current and future tools for evaluating patients at risk. It comprises 20 chapters by renowned international experts in the field of pressure ulcer research. Among them are representatives of the European and American Pressure Ulcer Advisory Panels, basic researchers, clinicians and tissue viability nurses. Topics range from economic and legal aspects to evidence-based knowledge on prevention and treatment, aetiology, risk assessment and future aspects of pressure ulcer management. .