Rho-modifying C3-like ADP-ribosyltransferases -- Large clostridial cytotoxins -- CNF and DNT -- Modulation of Rho GTPases by type III secretion system translocated effectors of Yersinia -- Pseudomonas aeruginosa ExoS and ExoT -- Pasteurella multocida toxin as a tool for studying Gq signal transduction -- Cytolethal distending toxins -- Anthrax toxins -- Uptake of binary actin ADP-ribosylating toxins -- The enteric toxins of Clostridium perfringens -- The Helicobacter pylori vacuoloating cytotoxin: from cellular vacuolation to immunosuppressive activities.