E Book

Adrenomedullin in Cardiovascular Disease

---

Biochemistry of Adrenomedullin -- Adrenomedullin Receptor and Signal Transduction -- Adrenomedullin Gene -- Adrenomedullin Expression and Secretion -- Biological Action of Adrenomedullin -- Circulating Adrenomedullin -- Role of Adrenomedullin in Cardiovascular Diseases -- Adrenomedullin as an Adipokine -- Adrenomedullin Knockout Mouse and Transgenic Mouse -- Pleiotropic Effect of Adrenomedullin: Lessons from Pure Adrenomedullin Knockout Mouse -- Therapeutic Application of Adrenomedullin -- Therapeutic Potentials of Adrenomedullin for Heart Failure and Pulmonary Hypertension.Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has a role in the pathogenesis of arteriosclerosis. Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease. Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.

---

Ketersediaan

Informasi Detail

Judul Seri

-

No. Panggil

-

Penerbit

Boston : Springer., 2005

Deskripsi Fisik

X, 219 p.online resource.

Bahasa

English

ISBN/ISSN

9780387254050

Klasifikasi

616.12

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

1st ed.

Subjek

Cardiology.

Info Detail Spesifik

-

Pernyataan Tanggungjawab

Toshio Nishikimi.

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar