Clinkal Issues and Tissue Processing -- Molecular Pathology Laboratory of the Future -- Clinical Utilities of Microdissected Samples -- Tissue Processing -- Sample Management and Tracking -- Methods of Tissue Microanalysis -- Tissue Microarrays -- Molecular Analysis of Microdissected Samples -- Methods of Microdissection and New Technologies -- Standard Diagnostic Techniques -- DNA Applications…
The Hedgehog Signaling Pathway in Cancer -- Rho GTPases and Cancer -- Developmental Biology of Fibroblasts and Neoplastic Disease -- The Extracellular Matrix During Normal Development and Neoplastic Growth -- Wilms’ Tumor: Starting Off the Kidney All Over Again? -- Testicular Teratomas: Back to Pluripotent Stem Cells -- Tumor Suppressors APC and VHL: Gatekeepers of the Intestine and Kidney --…
B Cell Development and Its Deregulation to Transformed States at the Pre-B Cell Receptor-Expressing Pre-BII Cell Stage -- Gene Expression Patterns in Human and Mouse B Cell Development -- New Insights into the Phenotype and Cell Derivation of B Cell Chronic Lymphocytic Leukemia -- Chronic Lymphocytic Leukemia: Molecular Genetics and Animal Models -- What Do Somatic Hypermutation and Class Switc…
Cancer Gene Therapy -- The Genetic Basis of Cancer -- Tumor Suppressor Gene Replacement for Cancer -- Antisense Technology -- Cancer Therapeutic Applications of Ribozymes and RNAi -- Fusogeneic Membrane Glycoproteins for Cancer Gene Therapy -- Suicide Gene Therapy -- Molecular Chemotherapy Approaches -- Genetic Immunotherapy Approaches -- Immunotherapy of Cancer by Dendritic Cell-Targeted Gene …
Disfunction of the Apoptotic Pathway in Cancer Cells -- Calcium Signaling and Apoptosis Resistance of Cancer Cells -- Cell Clearance and Cancer -- Specific, Pro-Poptotic Cell-Signaling: Design of Novel, Recombinant Targeted Antitumor Agents Operating Exclusively Through Modulation of Cellular Apoptotic Events -- Targeting Oncogenes Which Regulate Apoptosis -- Targeting Cyclins to Cause Cancer C…
Apoptotic Pathways and Their Regulation -- Mechanisms of Anticancer Drug Action -- Death Receptor Pathways As Targets for Anticancer Therapy -- Caspases; Modulators of Apoptosis and Cytokine Maturation — Targets for Novel Therapies -- The Intrinsic (Mitochondrial) Death Pathway and New Cancer Therapeutics: Bcl-2 Family in Focus -- Survivin, other IAPs, Smac/Diablo, and Omi/Htra2 — Modulatio…
Monitoring Antigen-Specific T Cell Responses -- Tumor Associated Antigens -- Immune Escape, Tumor induced immune suppression and immune escape: Mechanisms and Possible Solutions -- Virus Specific T-Cell Responses -- Cytotoxicity Assays Killer Lymphocytes in Cancer -- Monitoring T Cell Proliferation -- Elispot Assay, Assessment of Cellular Immune Responses to Anti-Cancer Vaccines -- Modified Eli…
Dawn of a new era in molecular cancer therapeutics -- Obtacles and opportunities in the clinical development of targeted therapeutics -- Tumor models for preclinical development of targeted agents -- Angiogenesis inhibitors: What is the clinical future? -- Epidermal growth factor receptor (EGFR) inhibitors in cancer therapy -- Cell survival signaling during apoptosis: Implications in drug resis…
Epidemiology, Biology, Genetics, and Pathology -- Epidemiology of Brain Tumors -- Molecular Genetics of Tumors of the Central Nervous System -- Molecular Pathology of Nervous System Tumors -- Genetic Modeling of Glioma Formation in Mice -- Biology of Brain Metastasis -- Analysis of Neural Precursor Cells in the Context of Origin of Brain Tumors, Their Treatment, and Repair of Treatment-Associat…