Medicinal chemistry of the disease modifying anti-rheumatic drugs -- Targeting DMARD therapy -- Pharmacoeconomic properties of disease-modifying antirheumatic drugs -- Future molecular targets -- Hydroxychloroquine -- Sulfasalazine -- Parenteral gold -- Azathioprine -- Methotrexate -- Leflunomide -- Cyclosporin -- Tetracyclines -- Systemic glucocorticoids in rheumatoid arthritis -- TNF-? inhibi…