An Introduction to Simulations as Scaffolds in Science Education -- Computer Simulations on a Multidimensional Continuum: A Definition and Examples -- Distinctions between Computer Simulations and Other Technologies for Science Education -- Inquiry-based Science Education and Problem Based Learning: Motivations, Objectives, and Challenges Relevant to Computer Simulations -- Scaffolding Science Learning: Promoting Disciplinary Knowledge, Science Process Skills, and Epistemic Processes -- Considerations for Integrating Simulations in the Science Classroom.This book outlines key issues for addressing the grand challenges posed to educators, developers, and researchers interested in the intersection of simulations and science education. To achieve this, the authors explore the use of computer simulations as instructional scaffolds that provide strategies and support when students are faced with the need to acquire new skills or knowledge. The monograph aims to provide insight into what research has reported on navigating the complex process of inquiry- and problem-based science education and whether computer simulations as instructional scaffolds support specific aims of such pedagogical approaches for students.