Basic Definitions and Introduction -- Natural Course of Wound Repair Versus Impaired Healing in Chronic Skin Ulcers -- Milestones in the History of Wound Healing -- Etiology and Mechanisms of Cutaneous Ulcer Formation -- Determining Etiology: History and Physical Examination -- Determining Etiology: Biopsy and Laboratory Investigation -- Ulcer Measurement and Patient Assessment -- Dressing Materials -- Debridement -- Antibiotics, Antiseptics, and Cutaneous Ulcers -- Topical Antibacterial Agents -- Skin Grafting -- Skin Substitutes and Tissue-Engineered Skin Equivalents -- Human Skin Equivalents: When and How to Use -- Growth Factors -- Drugs, Wound Healing and Cutaneous Ulcers -- Alternative Topical Preparations -- Additional Topical Preparations -- Nutrition and Cutaneous Ulcers -- Therapeutic Approach to Cutaneous Ulcers According to Appearance -- Appendix: Guidelines for Patients and Medical Staff.