E Book

Developmental Biology of Neoplastic Growth

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The Hedgehog Signaling Pathway in Cancer -- Rho GTPases and Cancer -- Developmental Biology of Fibroblasts and Neoplastic Disease -- The Extracellular Matrix During Normal Development and Neoplastic Growth -- Wilms’ Tumor: Starting Off the Kidney All Over Again? -- Testicular Teratomas: Back to Pluripotent Stem Cells -- Tumor Suppressors APC and VHL: Gatekeepers of the Intestine and Kidney -- Hormonal and Stromal Regulation of Normal and Neoplastic Prostatic Growth -- Neoplastic Growth Through the Developmental Stages of the Organism.In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence.

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Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

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No. Panggil

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Penerbit

Berlin, Heidelberg : Springer., 2005

Deskripsi Fisik

XII, 254 p. 23 illus., 7 illus. in color.online resource.

Bahasa

English

ISBN/ISSN

9783540276715

Klasifikasi

571.8

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

1st ed.

Subjek

Medical biochemistry.
Developmental biology.
Cell biology.
Cancer research.
Molecular biology.
Molecular Medicine.

Info Detail Spesifik

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Pernyataan Tanggungjawab

Alvaro Macieira-Coelho.

Versi lain/terkait

Lampiran Berkas

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