The discovery, development and novel actions of nimesulide -- Pharmacokinetics of nimesulide -- Pharmaceutical formulations of nimesulide -- Pharmacological properties of nimesulide -- Clinical applications of nimesulide in pain, arthritic conditions and fever -- Adverse reactions and their mechanisms from nimesulide.Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a c…
Structure and Function of the Immune System in Vertebrates -- Ontogeny and the Development of Cells Mediating Innate and Adaptive Immunity -- Phenotypic Characteristics of Neonatal B Cells -- Molecular Characteristics of the Neonatal B-Cell Repertoire -- Genetically Programmed Temporal Ordered Activation of Neonatal B-Cell Clones -- Antibody Responses in Fetuses and Newborns -- Effect of Matern…
Molecular Mimicry, Microbial Infection, and Autoimmune Disease: Evolution of the Concept -- The Structural Interactions Between T Cell Receptors and MHC-Peptide Complexes Place Physical Limits on Self-Nonself Discrimination -- A Virus-Induced Molecular Mimicry Model of Multiple Sclerosis -- Suppression of Autoimmunity via Microbial Mimics of Altered Peptide Ligands -- Molecular and Cellular Mec…
Diversity in Phagocytic Signaling -- Phagocytosis and Immunity -- Fc Receptor Phagocytosis -- Complement Receptors, Adhesion, and Phagocytosis -- Adding Complexity to Phagocytic Signaling: Phagocytosis-Associated Cell Responses and Phagocytic Efficiency -- Small GTP Binding Proteins and the Control of Phagocytic Uptake -- Regulation of Phagocytosis by Fc?RIIb and Phosphatases -- Phospholipases …
Innate Immunity in Autoimmune Diseases -- Innate Immunity in Experimental Autoimmune Myocarditis -- Toll-like Receptor 9 and Autoimmunity -- C-Reactive Protein as a Regulator of Autoimmune Disease -- NKT Cells and Autoimmune Type 1 Diabetes -- Genetics of Autoimmune Diseases -- The Genetics of Human Autoimmune Diseases -- Failure to Maintain T Cell DNA Methylation and Chromatin Structure Contri…
Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation -- Helix-Loop-Helix Proteins in Lymphocyte Lineage Determination -- Ikaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development -- Biochemistry of V(D)J Recombination -- The pre-B cell Receptor in B Cell Development: Recent Advances, Persistent Questions and Conserved Mec…
Viruses and the Innate Immune System -- How Viruses Elicit Interferon Production -- Genes Modulated by Interferons and Double-Stranded RNA -- Immunoevasive Strategies: Host and Virus -- Interferon Antagonists of Influenza Viruses -- The Anti-Interferon Mechanisms of Paramyxoviruses -- The Strategy of Conquest -- Immunomodulation by Poxviruses -- Interferon Antagonists Encoded by Emerging RNA Vi…
TIR Domain-Containing Adaptors Regulate TLR Signaling Pathways -- Toll-Like Receptors: Linking Innate and Adaptive Immunity -- Activation of Insect and Vertebrate Toll Signaling: From Endogenous Cytokine Ligand to Direct Recognition of Pathogen Patterns -- Genetic Analysis of Innate Immunity: Identification and Function of the TIR Adapter Proteins -- NF-?B, an Evolutionarily Conserved Mediator …
Principi fondamentali della biologia molecolare -- Il genoma umano -- Espressione e regolazione genica -- Ingegneria genetica -- Tecnologie molecolari e patologie umane -- Patologie infettive -- Patologie genetiche ereditarie -- Sistema immunitario e cellule del sangue -- Il cancro -- Terapie molecolari -- Conclusioni.Ecco finalmente disponibile in italiano un testo che sin dalla sua prima ediz…
Microenvironmental Effects on Tumour Progression and Metastasis -- Role of Microenvironment on Gene Expression, Angiogenesis and Microvascular Function in Tumors -- Imaging of Angiogenesis In Vivo with Fluorescent Proteins -- The Epigenetic Influence of the Tumor Microenvironment on Melanoma Plasticity -- Dynamics of Cell Adhesion Interactions during Melanoma Development -- Matrix Metalloprotei…